Fists of Fate is a Unique Gloves in Diablo IV Season 15 for All classes. It comes from General Unique pool; General Unique Pool - every Lair Boss (Initiate, Greater, Exalted, Belial) can drop it in addition to their dedicated table (one guide's Boss Loot Table Cheat Sheet).
Unique power
Your attacks randomly deal 1% to [250 - 300]% of their normal damage.
Affixes
+[6.0 - 8.0]% Lucky Hit Chance (6.0-8.0)
Where it drops
General Unique pool
General Unique Pool - every Lair Boss (Initiate, Greater, Exalted, Belial) can drop it in addition to their dedicated table (one guide's Boss Loot Table Cheat Sheet)